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Mixed Tocopherols (E 306)

Last reviewed October 19, 2026

In plain words: Mixed tocopherols (E 306) are forms of vitamin E added to keep fats from going rancid.

What the evidence review says

Mixed tocopherols are forms of vitamin E added to keep fats from going rancid. We found no notable concern at the levels used in food. EFSA did not set a daily intake limit because the available studies were limited.

No notable concern at the levels used to protect fats in food. EFSA did not set an ADI because the toxicology set was limited, and it said the dataset on the mixed extract and on gamma- and delta-tocopherol was too limited to carry the full assessment. The nutrient upper level for vitamin E is driven by slower blood clotting at high supplemental intakes of alpha-tocopherol, which is a different exposure from antioxidant use in food. EFSA's 2015 food-additive review still concluded that E306–E309 are not of safety concern at the levels used in food.

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This page is for general education. It is not medical advice and does not replace advice from your doctor, pediatrician, allergist or registered dietitian. Research changes; we review these pages when new evidence or rules come out. Last reviewed October 19, 2026.